Thursday 30 September 2010

'Extrapyramidal'

'Extrapyramidal' denotes CNS motor phenomena relating to the basal ganglia.

Basal ganglia's main components = SSSP: Striatum, subthalamic nucleus, substantia nigra, pallidum.

Extrapyramidal lesions cause abnormality with initiation and maintenance of movement. Extrapyramidal symptoms = tremor, rigidity, involuntary movements, dyskinesia (e.g. chorea, athetosis, ballismus, dystonia).
  • Dyskinesia = Difficulty or abnormality in performing voluntary muscular movements.
  • Chorea = Jerky, involuntary movements, chiefly of the face and extremities.
  • Athetosis = Slow, involuntary, wormlike movements of the fingers, toes, hands, and feet.
  • Ballismus = Twisting, shaking, and jerking motions.
  • Dystonia = Abnormal tone.

Symptoms NOT suggestive of extrapyramidal lesions =
  • Bradykinesia/akinesia (slow/absent movement)
  • Loss of postural reflexes.

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