Saturday 22 January 2011

SAH


Rx: Renounce raw conceit; find notes, morphine and pennies.
Refer neurosurgery
Reexamine CNS often
Chart BP, pupils, GCS
Fluids: SBP >160 (HHT = hypertensive hypervolaemic therapy... because hypotension causes vasospasm).
Nimodipine. Start by day 4 (asap on diagnosis!) till day 21 - three weeks.
Morphine + laxatives (opiates cause constipation).
Angiography: Sensitivity: 4 vessel angiography > CTA > MRA
Procedures: Clipping (craniotomy) or coiling (endovascular).

Tests
  • Angiogram: Sensitivity - 4 vessel angiography > CTA > MRA. CT detects >90% of SAHs.
  • LP: If CT negative and no c/i >12h after headache onset.
    Early CSF uniformly bloody; later CSF shows xanthochromia.

S&S
  • Thunderclap headache, vomiting, collapse, seizures, coma, neck stiffness, Kernig's sign, retinal or subhyaloid haemorrhage.
  • Focal signs at presentation may suggest site of aneurysm (e.g. pupil change suggests CNIII palsy suggests PCA aneurysm).
  • Sentinal headache due to small warning leak from the offending aneurysm.
DD of thunderclap headache = D SUMMIT V
Dissection of carotid/vertebral artery
SAH
Unknwon cause
Meningitis
Migraine
Intracerebral bleed
Thrombosis cortical vein
Valsalva maneuvre

Complications
  1. Rebleed.
  2. Vasospasm à stroke.
  3. Hydrocephalus.
  4. Hyponatraemia.
Prognosis
die immediately.
die within 1m from vasospasm or rebleed.
survive with or without neurological problems.

Grade I = No signs = 0% mortality.
Grade II = Necks stiffness, CN palsies = 11%.
Grade III = Drowsiness = 37%.
Grade IV = Drowsiness + hemiplegia = 71%.
Grade V = Prolonged coma = 100%.

Causes
Aneurysm rupture 80%.
AVM.
Unknown.

Risk factors
Smoking, hypertension, mycotic aneurysm, alcohol, bleeding disorder, low oestrogen (post-menopause).

Berry aneurysms are associated with:
  1. Polycystic kidneys.
  2. Coarctation of aorta.
  3. Ehlers-Danlos syndrome.

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